Truvda are two new antiviral drugs, emtricitabine and tenofovir, come together to form Truvada. Both emtricitabine and tenofovir are involved in the prevention of HIV cell multiplication within the body. While Truvada is not a cure for AIDA, it can be used to treat HIV in both children older than 12 and adults. Along with safe sex and the use of Truvada, the likelihood of becoming infected with HIV can be decreased to a large extent.
Following information includes information about Truvada, medical history, drug interactions, and other important details.
Truvada Medical History
For decades, doctors have used Truvada to suppress HIV in people who are already suffering from it. By blocking the enzyme, reverse transcriptase, Truvada can keep the HIV from copying its genetic material and thus, reproducing. Not only is it used to suppress HIV activity, Truvada is also effective in preventing the virus from infecting people.
It is especially useful for people who are at a higher risk of HIV infection, such as people practicing anal sex without a condom, who are diagnosed with an STD in the past six months or less and intravenous drug users who share their paraphernalia with others.
Mechanism of Action
Also known as a nuke, Tenofovir is actually an inhibitor for the enzyme nucleotide analogue reverse transcriptase. That means, it can prevent multiplication of the HIV by keeping the reverse transcriptase enzyme from working. Before HIV injects its genetic code –in the form of RNA– in an infected cell and replaces its genetic codes with the viral one, this enzyme changes it into DNA.
It has been reported that if a person takes Truvada daily, it can reduce the risk of HIV acquisition through sex by more than 92-95 percent! This was seen through a trial.
Truvada is A True Prophylactic
One of the very few drugs, Truvada can be called a true prophylactic since it is preventative in nature. You are not treating a disease through the intake of this medicine but preventing it from starting! People will tell you that kidney dysfunction and osteoporosis are the two major risks associated with this drug. However, the risk of these two disorders occurring in young people are very low.
Activation of Truvada’s Protective Function
The protective function of Truvada will kick in after it has been taken for a week or more. It has to be taken regularly and daily, if it is to be effective. With missed doses, the level of HIV protection derived from Truvada will decrease. Nevertheless, there is wiggle room and in case of a missed dose, it is recommended that the regular pill-taking schedule still be followed.
Of course, no one would want to continue taking a drug for the rest of their life, even one as effective as Truvada. However, before quitting cold turkey, it is recommended that you discuss this with your medical provider. Also, mention how your relationship status and/or sexual behaviors might have changed when discussing this with your doctor.
In order to avoid Truvada, it is better to use it with the following things in mind:
• Only use the amount prescribed by the doctor. Also, take care to follow all the directions that were mentioned.
• Using Truvada both with and without food is safe.
• Truvada should be used regularly for maximum benefit.
• With the use of the drug, you might also need frequent blood, kidney, and liver function, and bone mineral density tests.
• If you have hepatitis B you may develop liver symptoms after you stop taking this medication,
• In case, you miss a dose of Truvada, take it as soon as you remember. If, however, it is close to the time for your next scheduled dose, then you might want to skip it.
• Do not make up for the missed dose by taking extra medicine.
• Avoid driving or operating any kind of machinery after using this drug. This is because Truvada can make some people dizzy. Refrain from performing any kind of activity that requires alertness.
• Also, keep the intake of alcoholic beverages to a minimum when using Truvada.
Truvada Side Effects
• Losing strength
• Loss of weight
• Sour stomach
• Aching back
• Having difficulty in moving from one place to another
• Feeling discouraged
• Face feels as if burning
• Mouth feels as if burning
• Limbs feel tingly
• The feeling of pins and needles in the limbs
• Chest pain
• Loss of balance
• Sore throat
• stabbing pain
• weakness in the hands or feet
Besides being aware of the Truvada side effects, make sure that you take the following precautions:
If you are allergic to either emtricitabine or tenofovir, you should tell your doctor that before taking Truvada. Even if you are not allergic to this combo but have other allergies, let the doctor know about them. Always do that before using a drug that has been prescribed to you for the first time.
As with any other drug, if you are pregnant, then inform your doctor about it before using Truvada. However, if you have HIV, then your doctor might prescribe Truvada to you because it will decrease the risk of passing the virus to the baby. Again, do not use it without discussing it with your doctor.
Women who are breast-feeding should also avoid using Truvada since it can pass into breast milk. More importantly, HIV can also be transmitted via breast milk, thus women with HIV infection should not breast-feed.
The side effects caused by Truvada might increase, if it is taken in combination with certain other medicines. The specific drugs will be mentioned below, however, Truvada can interact with
• Antiviral medicine
• Antibiotics that are injected
• Bowel disorders medicine
• Medicine that is taken before organ transplant to reduce the likelihood of organ rejection
• Osteoporosis medication that is injected
• Arthritis medicine, such as